Clinical Trial Applications that Can Help Enhance Patient Recruitment

As clinical trials become increasingly complex, and the number of registered trials continues to grow, powerful real-world data (RWD) analytics are playing a crucial role in enabling data-driven decisions. These decisions can significantly accelerate and improve clinical trials by enhancing clinical trial patient recruitment.

At the forefront of this transformation are Site Explorer and Verana Trial Connect (VTC), which leverage comprehensive real-world datasets and intuitive user experiences to assist sponsors, contract research organizations (CROs), and clinicians in enhancing clinical trial patient recruitment and expanding opportunities for patients.

Revolutionizing Clinical Research with Real-World Data Analytics

Site Explorer and VTC are software as a service (SaaS) applications developed by Verana Health. By integrating high-quality data and secure and advanced technology, Verana Health aims to transform the clinical trials landscape, making it possible to reach more patients and accelerate treatment development in a cost-effective manner.

Site Explorer: Enhancing Site Selection for Clinical Trials

Site Explorer is an innovative site-selection application designed to provide trial sponsors and CROs a secure and efficient way to identify practices with specific patient populations that align with clinical trial requirements.

Site Explorer is an innovative site-selection application designed to provide trial sponsors and CROs a secure and efficient way to identify practices with specific patient populations that align with clinical trial requirements. Drawing from a vast amount of de-identified electronic health record data (EHR) from the American Academy of Ophthalmology IRIS^® Registry (Intelligent Research in Sight), the application offers valuable insights into the impact of inclusion and exclusion criteria on the eligible trial population. This information is crucial for informing trial design and ensuring that trials are representative of a diverse patient population.

Key features of Site Explorer include:

• Anonymized patient demographics
• Data from a wide range of community practices, ensuring a diverse pool of patients.
• Regularly refreshed information to strategically select sites with patients matched to study protocols.
• Access to practice-level details, such as research experience and clinician subspecialty.

Since its launch at the Drug Information Association (DIA) Global Annual Meeting in June 2023, the capabilities of Site Explorer have expanded. Users now benefit from extensive therapeutic-specific code lists for quick EHR data searches. Upcoming features for ophthalmology users will enable the development of cohorts that track eligible eyes, facilitating precise cohort creation based on laterality.

How Verana Trial Connect Streamlines Clinical Trial Patient Prescreening

VTC is a robust patient prescreening application that assists research teams in reviewing EHR information to identify eligible trial candidates and manage patient prescreening processes effectively.

While Site Explorer focuses on site selection, VTC is an application that empowers selected sites to accelerate clinical trial patient recruitment. VTC is a robust patient prescreening application that assists research teams in reviewing EHR information to identify eligible trial candidates and manage patient prescreening processes effectively. 

By leveraging both structured and unstructured EHR data, VTC automates the review of inclusion and exclusion criteria, resulting in a streamlined, accurate, and efficient prescreening workflow. This reduces administrative burden for clinicians and connects patients to innovative therapies through clinical trials.

Key features of Verana Trial Connect include:

• A viewable list of patients that may be good candidates, based on their clinical data.
• Convenience of sorting and filtering lists based on location, clinician, age, and last visit.
• An easy way of moving patients into potentially eligible and ineligible categories, and tracking and exporting reasons for ineligibility. 

Newly added to VTC is a feature that enhances communication within research teams via workflow applications, such as notes logs, and integrates next appointment data to prepare research teams for meetings with eligible patients.

Continuous Advancements in Clinical Research

As clinical trials grow in complexity and scale, the integration of RWD analytics through applications, such as Site Explorer and VTC, is essential.

In 2023, the FDA approved the second-highest number of drugs in 30 years, demonstrating the impact of ongoing advancements in clinical research. As the exclusive data curation and analytics partner of the IRIS Registry, Verana Health plays a pivotal role in helping drive this progress. 

The IRIS Registry – one of the largest specialty society clinical data registries in all of medicine – contains longitudinal de-identified patient data from 15,000 contributing clinicians. Refreshed monthly, this dataset provides comprehensive and timely insights into recruiting research study participants, enabling faster and more accurate site selection decisions.

As clinical trials grow in complexity and scale, the integration of RWD analytics through applications, such as Site Explorer and VTC, is essential. These applications not only enhance site selection and patient prescreening, but also ensure that clinical trials are inclusive and representative of broader patient populations. 

With Verana Health’s commitment to leveraging high-quality data and advanced technology, the future of clinical research looks promising, paving the way for faster, more effective treatments and improved patient outcomes.